Table 1

SSM in healthy subjects

Elastography techniqueMachine nameStudy participantsNumber of healthy volunteersAgeGender(M/F)SSReference
Transient elastographyFibroScanAdults1728 (25–33)5/1217.8 kPa (6.9–42.08) 13
FibroScanAdults5028.6±8.5 (16–50)30/2016.0±3.0 kPa (10.5–19.8) 14
FibroScanAdults4026.98±5.16N/A19.41±3.63 kPa 15
Shear wave elastographySWESuperSonic Imagine SAAdults5936 (21–80)25/3416.6±2.5 kPa 16
SuperSonic Imagine SAAdults17140.6±10.868/10317.3±2.6 kPa (8.05–24.9) 17
G4 xMATRIX iU22Children1467.47±3.39 (2–15)100/466.1±3.6 kPa (0.8–20.4) 18
Aplio 500 PlatinumChildren3711.6±4.9 (0.5–18)19/1816.8 kPa (1.6–22.8) 19
p-SWEPhilips Affiniti 70Adults10046±18 (18–87)49/5118.14±3.08 kPa (12.66–24.88) 20
Siemens Acuson S2000Adults9242.6±12.067/25From 2.39±0.34 m/s to 2.49±0.42 m/s 21
Siemens Acuson S2000Children388.07±0.7217/212.59±0.14 m/s 22
2D-SWELogiq E9 XDclearAdults6541.25±13.77 (18–87)31/3413.82±2.91 kPa 23
Acoustic radiation force impulseSiemens Acuson S2000Adults1634 (24–56)7/92.16 m/s (1.99–2.26) 24
Siemens Acuson S2000Adults2532.3 (22.1–63.0)11/142.46±0.35 m/s (breath hold after expiration) vs 2.66±0.36 m/s (deep inspiration) 25
Siemens Acuson S2000Adults15N/AN/A2.04±0.28 m/s 26
Siemens Acuson S2000Adults33N/AN/A2.2±0.31 m/s (1.6–3.3) 27
Siemens Acuson S2000Adults2032.9±9 (18–50)11/92.27±0.35 m/s (1.57–2.83) 28
Siemens Acuson S2000Children2028.1±4.792/1102.25±0.028 m/s 29
Siemens Acuson S3000Children1026±5.1 (8–17)32/702.43±0.31 m/s 30
Siemens Acuson S3000Children2410.5 (5.2, 15.0)12/122.53 m/s 31
Magnetic resonance elastographySigna HDxAdults1637±9 (28–56)9/73.565±0.586 kPa (2.353–4.442) 32
Signa HDxAdults1237 (25–82)9/33.6±0.3 kPa 32
  • 2D-SWE, two-dimensional shear wave elastography; F, female; M, male; N/A, not applicable; p-SWE, point shear wave elastography; SS, spleen stiffness; SSM, spleen stiffness measurement; SWE, shear wave elastography.